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Immortal Activated Human Hepatic Stellate Cells Generated by Ectopic Telomerase Expression

โœ Scribed by Schnabl, Bernd; Choi, Youkyung Hwang; Olsen, John C; Hagedorn, Curt H; Brenner, David A

Book ID
109886415
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
914 KB
Volume
82
Category
Article
ISSN
0023-6837

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## Abstract Normal somatic cells possess a finite life span owing to replicative senescence. Telomerase functions as a potential regulator of senescence in various cells. Expression level of human telomerase reverse transcriptase (hTERT) is correlated with telomerase activity and cellular immortali