✦ LIBER ✦

Immobilization of the knee joint alters the mechanical and ultrastructural properties of the rabbit anterior cruciate ligament

✍ Scribed by Peter O. Newton; Savio L-Y. Woo; Deidre A. MacKenna; Wayne H. Akeson

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 986 KB
Volume: 13
Category: Article
ISSN: 0736-0266
DOI: 10.1002/jor.1100130207

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The effects of immobilization of the knee joint on the mechanical and ultrastructural properties of the anterior cruciate ligament have not been well documented. Our goal was to determine these effects in a rabbit model and to assess the effect of knee flexion angle during immobilization. The knee joint was immobilized in either 170° or 105° of flexion, and new methodologies were utilized to determine the mechanical properties of the anterior cruciate ligament. In specimens from knees that had been immobilized, the cross‐sectional area of the ligament was 74% of the control value. The stress‐strain curve was altered slightly, and the strain at failure increased 32–40%. The modulus and stress at failure did not decrease significantly. There was no significant difference between the mechanical properties of the knees immobilized at 170° and 105° of flexion. Histological and ultrastructural evaluation demonstrated changes in the shape and intracellular makeup of the fibroblasts from the ligament after immobilization. This cellular response may account for the alterations in the mechanical properties of the anterior cruciate ligament.

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