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Immobilization of gene vectors on bisphosphonate-mediated gene-eluting metal stents using antibody for localized gene delivery

โœ Scribed by Yong Wang; Mei Yu; Linhua Zhang; Cunxian Song; Ivan S. Alferiev; Robert J. Levy


Book ID
113694783
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
248 KB
Volume
152
Category
Article
ISSN
0168-3659

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## Abstract ## Background Conventional strategies of gene therapy using viral vectors result in suboptimal localization and potentially dangerous distal spread of vector. We hypothesized that localized delivery of adenoviral gene vectors could be achieved from a polyurethane (PU) film through a me