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Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K2P) and voltage-gated (Kv1.1 and Kv1.2) potassium channels

✍ Scribed by Lee, Jaekwang; Kim, Taekeun; Hong, Jinpyo; Woo, Junsung; Min, Hyunjung; Hwang, Eunmi; Lee, Sung; Lee, C Justin


Book ID
115022740
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
278 KB
Volume
8
Category
Article
ISSN
1744-8069

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## Abstract The stimulation of cell proliferation by insulin like growth factor IGF‐1 has previously been shown to depend on activation of voltage gated K^+^ channels. The signaling involved in activation of voltage gated K^+^ channel Kv1.3 includes the phosphatidylinositol‐3 (PI3) protein kinase,