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Imino ene-type reaction of enamines with N-sulfonylimines and application to diastereoselective synthesis of N-sulfonyl-1,3-diamines

✍ Scribed by Ito, Mai; Kashiwagi, Takeru; Kotani, Shunsuke; Nakajima, Makoto; Sugiura, Masaharu


Book ID
124142060
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
720 KB
Volume
55
Category
Article
ISSN
0040-4039

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## Abstract Deprotonation of the chiral __N__‐(__tert__‐butylsulfinyl) ketimine **1** followed by trapping with imines **2** afforded the β‐aminoimines **3** as the Mannich‐type products in high diastereoselectivities (99:1 __dr__). As versatile synthons chiral β‐amino imines **3** could be transfo