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Imidazolium-based phosphinite ionic liquid as reusable catalyst and solvent for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)- (thio)ones

✍ Scribed by Hassan Valizadeh; Abbas Shockravi


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
86 KB
Volume
20
Category
Article
ISSN
1042-7163

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✦ Synopsis


A mild and efficient procedure for the synthesis of 3,4-dihydropyrimidin-2(1H)-(thio)ones in phosphinite ionic liquid is described. This ionic liquid plays a dual role as both the reaction media and also a catalyst, which can be easily recovered and reused in several runs.


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## Abstract An efficient solvent‐free method for the synthesis of various 3,4‐dihydropyrimidin‐2(1__H__)‐ones using TiO~2~ as a recyclable heterogeneous catalyst is described. Compared to known methods, satisfactory results are obtained with excellent yields, short reaction times, and simplicity in