## Abstract For Abstract see ChemInform Abstract in Full Text.
Imidazole Derivatives as New Potent and Selective 20-HETE Synthase Inhibitors.
β Scribed by Toshio Nakamura; Hiroyuki Kakinuma; Hiroki Umemiya; Hideaki Amada; Noriyuki Miyata; Kazuo Taniguchi; Kagumi Bando; Masakazu Sato
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 125 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A series of substituted 2iminopyrrolidines is prepared and evaluated as selective inhibitors of the human inducible isoform of nitric oxide synthase (NOS). The most potent analogue is (VI). The compound (+)-(VIII) is also a good inhibitor of human inducible NOS and potent in vivo in mouse models of