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IMDA Cycloadditions of 3-Alkynyl Tethered 2-Pyrones for the Synthesis of Medium-Sized Macrocycles.

โœ Scribed by Jeong-Taek Shin; Seunghoon Shin; Cheon-Gyu Cho


Book ID
101967643
Publisher
John Wiley and Sons
Year
2004
Weight
33 KB
Volume
35
Category
Article
ISSN
0931-7597

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Dielsโ€“Alder cycloadditions of 3,5-dibrom
โœ Cheon-Gyu Cho; Yong-Woo Kim; Won-Kyum Kim ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 56 KB

Dibromo-2-pyrone underwent facile Diels-Alder [4+2] cycloadditions with cycloalkenyl silyl ethers to provide a series of tricyclolactones, with good to excellent chemical yields and stereoselectivity. The resulting cycloadducts could be readily converted into the corresponding bicarbocycles upon sel