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IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer

โœ Scribed by Roy S. Herbst; Waun Ki Hong


Book ID
114105507
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
520 KB
Volume
29
Category
Article
ISSN
0093-7754

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Anti-epidermal growth factor receptor-an
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Recent studies demonstrated that tumors overexpressing the epidermal growth factor receptor (EGF-R, erbB-1) are associated with poor clinical outcome. This led to the development of a variety of monoclonal antibodies targeting the extracellular domain of this receptor tyrosine kinase. The aim of our