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Imbalanced Expression of Inhibin and Activin Subunits in Primary Epithelial Ovarian Cancer

✍ Scribed by Wenxin Zheng; Michelle P. Luo; Corrine Welt; Geralyn Lambert-Messerlian; C.James Sung; Zhong Zhang; Shao-yao Ying; Alan L. Schneyer; Stuart C. Lauchlan; Juan C. Felix


Book ID
112247332
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
538 KB
Volume
69
Category
Article
ISSN
0090-8258

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Activins and inhibins belong to the transforming growth factor-␀ (TGF-␀) superfamily of multifunctional cytokines that bind to transmembrane receptors with serine/threonine kinase activity. In this study, we characterized the levels of expression of 3 activin/inhibin subunits (␀A, ␀B, ␣), and 2 type