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Imbalanced cytokine production by macrophages from autoimmune-prone mice

✍ Scribed by Jerrold Levine; Daqing Hartwell; David I. Beller


Book ID
104177385
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
911 KB
Volume
30
Category
Article
ISSN
0165-2478

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Splenocytes from young adult or old C57BUGNNia mice were stimulated in vitro with the anti-CD~E mAb, 145-2C11, in either soluble (2C11 s) or plate-bound (2C11 i) form. In the young group, each mode of cell activation resulted in peak DNA synthesis at -48 h of culture; at this time point, the old gro