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Imbalance of the C4A and C4B genes dosage as a robust risk factor for premature cardiovascular disease morbidity and mortality

✍ Scribed by George Füst; Mária Sasvári; Bernadett Blaskó; Csaba Szalai; Róza Ádány; C.-Yung Yu; Gudmundur J. Arason


Book ID
116755997
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
77 KB
Volume
44
Category
Article
ISSN
0161-5890

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## Abstract Most tests of association between DNA sequence variation and quantitative phenotypes in samples of randomly chosen individuals rely on specification of genotypic strata followed by comparison of phenotypes across these strata. This strategy often succeeds when phenotypic differences are