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Imbalance of purine nucleotides in alanosine-resistant baby hamster kidney cells

✍ Scribed by Jesse C. S. Pang; Run Pun Du; Hermine Bingham; Peter Juranka; Voon -Loong Chan

Book ID
112557844
Publisher
Springer
Year
1989
Tongue
English
Weight
711 KB
Volume
15
Category
Article
ISSN
1572-9931

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## Abstract A novel synergistic effect of the antitumor agent alanosine (2‐amino‐3‐(hydroxynitrosoamino) propionic acid), which specifically inhibits the enzyme adenylosuccinate synthetase (ASS) and guanine on the growth of Chinese hamster ovary (CHO) cells and human diploid fibroblasts (HDF) has b