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Imatinib mesylate lacks activity in small cell lung carcinoma expressing c-kit protein : A Phase II clinical trial

✍ Scribed by Lee M. Krug; John P. Crapanzano; Christopher G. Azzoli; Vincent A. Miller; Naiyer Rizvi; Jorge Gomez; Mark G. Kris; Barbara Pizzo; Leslie Tyson; Megan Dunne; Robert T. Heelan

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 80 KB
Volume: 103
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.21000

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## Abstract ## BACKGROUND The objective of this study was to evaluate the feasibility, toxicity, and efficacy of a novel three‐drug regimen containing paclitaxel, carboplatin, and topotecan followed by oral etoposide in the first‐line treatment of patients with small cell lung carcinoma. ## METHO