## Abstract ## BACKGROUND Initial treatment for adult patients with Philadelphia chromosomeβpositive (Ph[+]) chronic myelogenous leukemia (CML) now includes imatinib mesylate. However, to our knowledge, there are few data regarding imatinib safety, efficacy, and response monitoring in patients age
Imatinib mesylate-induced molecular remission of Philadelphia chromosome-positive myelodysplastic syndrome
β Scribed by Drummond, M W; Lush, C J; Vickers, M A; Reid, F M; Kaeda, J; Holyoake, T L
- Book ID
- 110055369
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 145 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0887-6924
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π SIMILAR VOLUMES
## Abstract ## BACKGROUND. The prognosis of patients with chronic myelogenous leukemia (CML) after failure of imatinib mesylate therapy is not well documented. ## METHODS. The outcome of 420 patients with CML postβimatinib failure (resistanceβrecurrence in 374; toxicities in 46) were reviewed in
The addition of imatinib to high-intensity chemotherapy has improved the outcome of patients with Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (ALL). However, the possible long-term side effects of this combination are not yet known. Development of new clonal abnormalities in c