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Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB

✍ Scribed by S. Houle; N. Ginovart; D. Hussey; J.H. Meyer; A.A. Wilson

Publisher
Springer
Year
2000
Tongue
English
Weight
115 KB
Volume
27
Category
Article
ISSN
0340-6997

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## Abstract The highly potent serotonin (5‐HT) uptake blocker, McN‐5652‐Z (__trans__‐1,2,3,5,6,10b ‐ hexahydro ‐ 6 ‐ [4 ‐ (methylthio)phenyl] pyrrolo ‐ [2,1‐a]‐isoquinoline) was labeled with ^11^C for studying serotonin uptake sites using positron emission tomography (PET). [^11^C]McN‐5652‐Z was sy