<span>The book covers all aspects of one of the most advanced magnetic resonance imaging techniques, namely Diffusion Tensor Imaging (DTI) and Fractional Anisotropy (FA) values in early Parkinson’s disease (PD) patients. It provides step-by-step descriptions of DTI and its use in the early diagnosis
Imaging in Parkinson's Disease
✍ Scribed by David Eidelberg
- Publisher
- Oxford University Press, USA
- Year
- 2011
- Tongue
- English
- Leaves
- 221
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
✦ Synopsis
Imaging in Parkinson's Disease provides up-to-date information concerning new applications of brain imaging to the study of Parkinson's disease. Written by experts in the field, the book focuses on structural and functional imaging methodologies that have recently been applied to study the natural history of Parkinson's disease, with emphasis on the development of the major motor manifestations of the illness as well as cognitive impairment and dementia. Individual chapters address the role of imaging in differential diagnosis and in the evaluation of pharmacologic and surgical treatment effects. In-depth discussion of the use of imaging tools to study disease mechanisms is also provided, with emphasis on the roles of neuroinflammation, protein aggregation, and abnormal network organization in parkinsonism. Additionally, the text covers a number of relevant novel topics including recent advances in volumetric and functional MRI, echosonography, dopaminergic and cholinergic neurotransmitter imaging, and applications to experimental interventions such as gene therapy and transplantation. Covering a wide range of subjects and beautifully illustrated, Imaging in Parkinson's Disease is a valuable reference for neurologists, neurosurgeons and neuropsychologists, and a helpful resource for students engaged in postgraduate biomedical and clinical training.
✦ Table of Contents
Table of Contents......Page 10
Acknowledgment......Page 12
Contributors......Page 14
1. DOPAMINERGIC IMAGING IN PARKINSON’S DISEASE: PET......Page 18
2. DOPAMINERGIC IMAGING IN PARKINSON’S DISEASE: SPECT......Page 26
3. CEREBRAL GLUCOSE METABOLISM AND BLOOD FLOW IN PARKINSON’S DISEASE......Page 36
4. STRUCTURAL ABNORMALITIES IN PARKINSON’S DISEASE: MRI AND RELATED METHODS......Page 47
5. TRANSCRANIAL SONOGRAPHY IN PARKINSONIAN SYNDROMES......Page 66
6. PARKINSONIAN TREMOR......Page 79
7. ATYPICAL PARKINSONIAN SYNDROMES......Page 88
8. BRAIN ACTIVATION STUDIES IN PARKINSON’S DISEASE......Page 103
9. FUNCTIONAL MARKERS OF COGNITION IN PARKINSON’S DISEASE: [sup(18)]F-FDG AND H[sub(2)][sup(15)]O POSITRON EMISSION TOMOGRAPHY STUDIES......Page 114
10. IMAGING COGNITIVE DYSFUNCTION IN PARKINSON’S DISEASE: CHOLINERGIC NEUROTRANSMISSION AND PROTEIN AGGREGATION......Page 123
11. IMAGING INFLAMMATION IN PARKINSONIAN SYNDROMES......Page 142
12. FUNCTIONAL IMAGING BIOMARKERS FOR THE ASSESSMENT OF PARKINSON’S DISEASE PROGRESSION......Page 148
13. EFFECTS OF TREATMENT: PHARMACOLOGIC......Page 159
14. NEUROIMAGING IN LEVODOPA-INDUCED DYSKINESIA......Page 171
15. EFFECTS OF SURGICAL TREATMENT......Page 180
16. CELL-BASED THERAPIES: IMAGING OUTCOMES......Page 188
17. IMAGING APPLICATIONS TO PARKINSON’S DISEASE CLINICAL TRIALS......Page 196
18. CLINICAL APPLICATIONS......Page 206
D......Page 218
M......Page 219
R......Page 220
W......Page 221
📜 SIMILAR VOLUMES
Parkinson's disease and parkinsonism are particular problems in the elderly, causing disability and impairing quality of life. This book covers the clinical features, diagnosis, and management of Parkinson's disease in elderly people, discussing such topics as motor symptoms, depression, and autonom
<P>In this exciting and timely book new approaches to repairing the parkinsonian brain are described by leading experts. Never in history has there been greater hope that novel experimental therapies can support significant restoration of brain function. This book gives an overview of the current st