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Imaging dynamics of CD11c+cells and Foxp3+cells in progressive autoimmune insulitis in the NOD mouse model of type 1 diabetes

✍ Scribed by Schmidt-Christensen, Anja; Hansen, Lisbeth; Ilegems, Erwin; Fransén-Pettersson, Nina; Dahl, Ulf; Gupta, Shashank; Larefalk, Åsa; Hannibal, Tine D.; Schulz, Alexander; Berggren, Per-Olof; Holmberg, Dan

Book ID
121607719
Publisher
Springer
Year
2013
Tongue
English
Weight
878 KB
Volume
56
Category
Article
ISSN
0012-186X

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✍ Hiroo Toyoda; Bent Formby 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB 👁 2 views

The nonobese diabetic (NOD) mouse spontaneously develops an autoimmune diabetes that shares many immunogenetic features with human insulin-dependent diabetes mellitus (IDDM), type 1 diabetes. The mononuclear cell infiltrates in the islet, which results in the development of insulitis (a prerequisite