Imaging [18F]FAU [1-(2′-deoxy-2′-fluoro-beta-D-arabinofuranosyl) uracil] in dogs
✍ Scribed by Haihao Sun; Jerry M Collins; Thomas J Mangner; Otto Muzik; Anthony F Shields
- Book ID
- 117687891
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 140 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0969-8051
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📜 SIMILAR VOLUMES
The reaction of [2-14C]-2 ,4-bis-O-(trimethylsilyl)uracil (2) with ~-~-acetyl-~-0-benzoyl-2-deoxy-2-fluoro-~-D-arabinofuranosyl bromide (3) yielded the 3-O-acety1-5-0-benzoyl nucleos e 4 which was hydrolyzed with methanolic ammonia to afford [ 2-feC]-T-( 2-deoxy-2fluoro-p-D-arabinofuranosy1)uracil (
The synthesis of t h e title canpound (7) is described. [2-14C] cytosine (I) is treated with an aqueous mixture of sodium bisulfite and sodium sulfate at 8OoC for 30 rnin. The resulting solid is then treated with aqueous sodiun hydroxide and passed through a cation exchange colunn, producing [ Z-14C