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IL4-589C/T polymorphism and IgE levels in severe malaria

✍ Scribed by Federica Verra; Gaia Luoni; Carlo Calissano; Marita Troye-Blomberg; Peter Perlmann; Hedvig Perlmann; Bruno Arcà; Bienvenu Sodiomon Sirima; Amadou Konaté; Mario Coluzzi; Dominic Kwiatkowski; David Modiano

Book ID
116181548
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
69 KB
Volume
90
Category
Article
ISSN
0001-706X

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## Abstract The clinical course and outcome of HIV‐1 infection are highly variable among individuals. Interleukin 4 (IL‐4) is a key T helper 2 cytokine with various immune‐modulating functions including induction of immunoglobulin E (IgE) production in B cells, downregulation of CCR5 and upregulati