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IL10 polymorphisms, rhinovirus-induced bronchiolitis, and childhood asthma

✍ Scribed by Koponen, Petri; Karjalainen, Minna K.; Korppi, Matti

Book ID: 119286993
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 56 KB
Volume: 131
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2012.10.049

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IL10 is an anti-inflammatory cytokine that has been found to have lower production in macrophages and mononuclear cells from asthmatics. Since reduced IL10 levels may influence the severity of asthma phenotypes, we examined IL10 singlenucleotide polymorphisms (SNPs) for association with asthma sever