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IL-6 signaling via the STAT3/SOCS3 pathway: Functional Analysis of the Conserved STAT3 N-domain

✍ Scribed by Ling Zhang; Donna B. Badgwell; Jack J. Bevers; Karni Schlessinger; Peter J. Murray; David E. Levy; Stephanie S. Watowich


Book ID
106457922
Publisher
Springer
Year
2006
Tongue
English
Weight
345 KB
Volume
288
Category
Article
ISSN
0300-8177

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator