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IL-4 mediates dicloxacillin-induced liver injury in mice

✍ Scribed by Satonori Higuchi; Masanori Kobayashi; Yukitaka Yoshikawa; Koichi Tsuneyama; Tatsuki Fukami; Miki Nakajima; Tsuyoshi Yokoi


Book ID
116923718
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
932 KB
Volume
200
Category
Article
ISSN
0378-4274

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The liver appears to play an important role in immunological tolerance, for example, during allo-transplantation. We investigated tolerance mechanisms in the model of concanavalin A (ConA)-induced immune-mediated liver injury in mice. We found that a single injection of a sublethal ConA dose to C57B