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IL-23 is Required for Induction of an Innate Immune Response to Citrobacter Rodentium

✍ Scribed by Darrell O'Quinn; Trenton Schoeb; Casey Weaver


Book ID
113539531
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
44 KB
Volume
123
Category
Article
ISSN
1090-2341

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We have investigated the importance of endogenously produced IL-12 in innate and adaptive immunity to tumor transplants. The immunogenic lymphoma RMA and its TAP-deficient variant RMA-S were tested for rejection responses by normal and IL-12-deficient mice. IL-12 was crucial for the immunity induced