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IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade

✍ Scribed by Anupam Mitra; Smriti Kundu Raychaudhuri; Siba P. Raychaudhuri


Book ID
119224899
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
586 KB
Volume
60
Category
Article
ISSN
1043-4666

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Longitudinal inhibition of PI3K/Akt/mTOR
✍ Takayuki Ikezoe; Chie Nishioka; Kentaro Bandobashi; Yang Yang; Yoshio Kuwayama; πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 1006 KB

This study found that phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling was activated in human T-cell lymphotropic virus type I (HTLV-1)-infected leukemia cells. Rapamycin (1-100 nM, 48 h), the inhibitor of mTOR and its analog RAD001 (1-100 nM, 48 h)-induced gro