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IL-22 Enhances CCL20 Production in IL-1β-Stimulated Human Gingival Fibroblasts

✍ Scribed by Hosokawa, Yoshitaka; Hosokawa, Ikuko; Shindo, Satoru; Ozaki, Kazumi; Matsuo, Takashi

Book ID: 125361141
Publisher: Springer
Year: 2014
Tongue: English
Weight: 359 KB
Volume: 37
Category: Article
ISSN: 0360-3997
DOI: 10.1007/s10753-014-9939-5

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## Abstract Periodontitis is a chronic bacterial infection of tooth‐supporting structures. T‐helper type 1 (Th1) cells are related to the exacerbation of periodontal disease. Human gingival fibroblasts (HGFs), the major cell type in periodontal connective tissues, are involved in immunological resp