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IL-1α stimulated TNFα production by cultured human proximal tubular epithelial cells

✍ Scribed by Yard, Benito A; Daha, Mohamed R; Kooymans-Couthino, Mariska; Bruijn, Jan A; Paape, Marion E; Schrama, E; van Es, Leendert A; van der Woude, Fokko J


Book ID
109882141
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
845 KB
Volume
42
Category
Article
ISSN
0085-2538

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Human bone marrow stromal cells repond to stimulation by the monokines IL-1 and TNF by producing colony-stimulating factors such as GM-CSF and G-CSF. In this study we show that I L -l a and TNFa act synergistically to stimulate GM-CSF and G-CSF production by cultured marrow stromal cells. We further