IL-1R3: A neuronal specific IL-1 receptor?
β Scribed by N. Quan; Q. Li; L. Zhu; Q. Chen; H. Zhang; F. Zhao; S. Herness; D. Wu
- Book ID
- 116276889
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 35 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0889-1591
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Three molecular forms of the IL-1 receptor antagonist (IL-1ra) have been identified and cloned. Secreted IL-1ra (sIL-1ra or IL-1ra1) contains a classical leader peptide giving a released mature protein. Two intracellular isoforms, icIL-1ra type I (IL-1ra2) and icIL-1ra type II (IL-1ra3), have no lea