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IL-18 gene promoter polymorphism is involved in HIV-1 infection in a Brazilian pediatric population

✍ Scribed by Ludovica Segat; Daiana Bevilacqua; Michele Boniotto; Luiz C. Arraes; Paulo R. de Souza; Josè L. de Lima Filho; Sergio Crovella


Book ID
105947736
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
72 KB
Volume
58
Category
Article
ISSN
0093-7711

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## Abstract Polymorphisms in genes responsible for maintaining genomic integrity are potential modifiers of disease risk. Since considerable interindividual and interethnic variation in DNA repair capacity has been associated with polymorphic alleles, we evaluated the frequency of the 2R/3R variant