Nicotinamide prevents the development of
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O'Brien, Bronwyn A.; Harmon, Brian V.; Cameron, Donald P.; Allan, David J.
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Article
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2000
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John Wiley and Sons
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English
β 195 KB
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The development of diabetes in non-obese diabetic (NOD) mice, which normally takes between 3 and 7 months, can be accelerated by cyclophosphamide (CY) injections, with rapid progression to diabetes within only 2Β±3 weeks. This insulin-dependent diabetes mellitus (IDDM) can be prevented or delayed in