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IL-17 Eliminates the Therapeutic Effects of Myelin Basic Protein-Induced Nasal Tolerance in Experimental Autoimmune Encephalomyelitis by Activating IL-6

✍ Scribed by G.-Y. Wang; B. Sun; Q.-F. Kong; Y. Zhang; R. Li; J.-H. Wang; D.-D. Wang; G. X. Lv; H.-L. Li

Book ID
110861694
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
390 KB
Volume
68
Category
Article
ISSN
0300-9475

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We have produced T cell lines with a Th2 phenotype in the presence of IL-4 and the glucocorticoid dexamethasone (DEX). IL-4 and DEX together were more effective in inducing a Th2 response than IL-4 alone. Myelin basic protein (MBP)-specific Th2 lines were obtained and their ability to induce experim