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IL-16 signaling specifically induces STAT6 activation through CD4

✍ Scribed by Changbao Liu; Juliane Mills; Ken Dixon; Joseph Vennarini; Mark Cunningham; Alfred Del Vecchio; Anuk Das; William Glass


Book ID
116397879
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
332 KB
Volume
38
Category
Article
ISSN
1043-4666

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## Abstract Microglia, the resident macrophage of the brain, mediates immune and inflammatory responses in the central nervous system (CNS). Activation of microglia and secretion of inflammatory cytokines associate with the pathogenesis of CNS diseases, including multiple sclerosis (MS), Alzheimer'