Polyethylenimine-based antisense oligode
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Ji-Hye Seong; Kyung-Mi Lee; Sung Tae Kim; Su-Eon Jin; Chong-Kook Kim
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Article
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2006
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John Wiley and Sons
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English
β 294 KB
## Abstract ## Background Interleukinβ4 (ILβ4) plays a crucial role as an inflammatory mediator in allergic asthma via inducing Th2 inflammation and IgE synthesis. To develop an effective therapeutic agent which specifically inhibits production of ILβ4, antisense oligodeoxynucleotides (ASβODNs) ag