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IL-11 mediated Stat3 activation in inflammation and cancer

โœ Scribed by Tracy Putoczki; Stefan Thiem; Andrew Jarnicki; Brent Mckenzie; Stefan Rose-John; Matthias Ernst


Book ID
116398857
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
111 KB
Volume
48
Category
Article
ISSN
1043-4666

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โœ Spiotto, Michael T.; Chung, Theodore D.K. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

## Background: In the human prostate cancer cell line lncap, interleukin (il)-6 has been shown to regulate both growth and neuroendocrine (ne) differentiation. we recently observed that il-6 mediated growth arrest in lncap by activating stat 3. since differentiation and growth arrest are often asso