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IL-10 Secretion and Sensitivity in Normal Human Intestine and Inflammatory Bowel Disease

✍ Scribed by Christoph Gasche; Silvia Bakos; Clemens Dejaco; Wolfgang Tillinger; Schaker Zakeri; Walter Reinisch


Book ID
110239455
Publisher
Springer
Year
2000
Tongue
English
Weight
116 KB
Volume
20
Category
Article
ISSN
0271-9142

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Background: Wnt signaling regulates intestinal epithelial stem cell function. Wnt ligands bind Frizzled (Fz) receptors and lowdensity lipoprotein-receptor-related protein (LRP) 5 and 6. Secreted Frizzled-related protein (SFRP) and Dickkopf families inhibit Wnt signaling. Our aim was to study express