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IL-10 production in non–small cell lung carcinoma patients is regulated by ERK, P38 and COX-2

✍ Scribed by Swati Patel; Shamal Vetale; Pradeep Teli; Rajesh Mistry; Shubhada Chiplunkar


Book ID
114778953
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2012
Tongue
English
Weight
534 KB
Volume
16
Category
Article
ISSN
1582-1838

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## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in