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IL-10 mediates susceptibility to Leishmania donovani infection

✍ Scribed by Michaela L. Murphy; Ulrike Wille; Eric N. Villegas; Christopher A. Hunter; Jay P. Farrell

Book ID: 101384225
Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 262 KB
Volume: 31
Category: Article
ISSN: 0014-2980
DOI: 10.1002/1521-4141(2001010)31:10<2848::aid-immu2848>3.0.co;2-t

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## Abstract Mice from most inbred strains are resistant to infection with __Leishmania major__ whereas mice from BALB strains are highly susceptible. Resistance and susceptibility result from the development of Th1 or Th2 cells, respectively. In this report, we document an IL‐2 mRNA burst, precedin