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IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway

✍ Scribed by Andrea Joss; Mübeccel Akdis; Alexander Faith; Kurt Blaser; Cezmi A. Akdis


Book ID
101382319
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
118 KB
Volume
30
Category
Article
ISSN
0014-2980

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al