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IL-10 deficiency reduces Helicobacter pylori gastric colonization in C57BL/6 mice

✍ Scribed by Mark T. Whary; Barbara J. Sheppard; Jennifer Cline; Sandy Xu; James G. Fox


Book ID
119429352
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
434 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract The BALB/c‐IL10 null mouse strain develops colitis and colitis‐associated adenocarcinomas, and is a model for idiopathic inflammatory bowel disease. We tested the hypotheses that (__i__) azoxymethane (AOM), a carcinogen that targets the colon, synergizes with the colonic inflammation in