Protein kinase C activation by interleuk
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Osamu Kozawa; Atsushi Suzuki; Haruhiko Tokuda; Takehiro Kaida; Toshihiko Uematsu
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Article
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1997
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John Wiley and Sons
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English
β 100 KB
π 2 views
We investigated the regulatory mechanism of interleukin-6 (IL-6) synthesis induced by interleukin-1 (IL-1) in osteoblast-like MC3T3-E1 cells. IL-1 stimulated the secretion of IL-6 in a dose-dependent manner in the range between 0.1 and 100 ng/ml. Staurosporine and calphostin C, inhibitors of protein