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Ikaros family transcription factors in chronic and acute leukemia

✍ Scribed by Maja Matulic; Mladen Paradzik; Lipa Cicin-Sain; Sanja Kapitanovic; Klara Dubravcic; Drago Batinic; Mariastefania Antica

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
391 KB
Volume
84
Category
Article
ISSN
0361-8609

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The POU (Pit-Oct-Unc) family of transcription factors was originally defined on the basis of a common DNA binding domain in the mammalian factors Pit-1, Oct-1, and Oct-2 as well as the nematode protein Unc-86. Subsequently, a number of other POU family factors have been identified in both vertebrate