✦ LIBER ✦

IGPHARM: Interactive graphic package for pharmacokinetic analysis

✍ Scribed by Carla Gomeni; Roberto Gomeni

Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 769 KB
Volume: 11
Category: Article
ISSN: 0010-4809
DOI: 10.1016/0010-4809(78)90017-4

No coin nor oath required. For personal study only.

✦ Synopsis

An interactive graphic software package for pharmacokinetic analysis of data is presented. These programs, with the help of graphic computing techniques, allow the determination of pharmacokinetic parameters (transfer rate constants, disposition constants, volume of distribution, total body clearance, area under time-concentration curve, half-life, etc.) for one-, two-, and three-compartment open models, after intravenous or extravascular dose administration. Using the parameters obtained after a single-dose administration it is also possible to simulate numerically and graphically the time-concentration curve after different doses administered at different time intervals.

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