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IgG vs IgE: Mediators of antigen-induced guinea pig tracheal contraction

✍ Scribed by Jean F. Regal


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
708 KB
Volume
8
Category
Article
ISSN
0162-3109

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Antigen (ovalbumin)-induced contraction of guinea-pig isolated trachea, which largely resulted from the endogenous release of peptidoleukotrienes, was strongly inhibited by the non-selective phosphodiesterase (PDE) inhibitor theophylline and, more potently, by the selective PDE type IV inhibitors ro