IgG subclass of anti-HSV antibodies following neonatal HSV infections

✍ Scribed by A. Hayward; M. Herberger; L. Corey

• Book ID: 104774208
• Publisher: Springer
• Year: 1986
• Tongue: English
• Weight: 179 KB
• Volume: 145
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00439394

✦ Synopsis

Ten survivors of neonatal HSV encephalitis had IgG1 and IgG3 antibodies to HSV 6 or more months after their infection. Six had IgG4 antibodies but only one had IgG2 antibodies. Titers of anti-HSV antibodies were similar following neonatal and later HSV infections. Antibody deficiency is thus not part of the selective deficiency of HSV-specific immunity following neonatal infection.