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IgG-binding factors and polyclonal activation of human B cells

โœ Scribed by Revillard, Jean-Pierre; Bich-Thuy, Ph.D., Le Thi


Book ID
122578000
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
511 KB
Volume
4
Category
Article
ISSN
0197-1859

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Production of antibodies can last for a lifetime, through mechanisms that remain poorly understood. Here, we show that human memory B lymphocytes proliferate and differentiate into plasma cells in response to polyclonal stimuli, such as bystander T cell help and CpG DNA. Furthermore, plasma cells se