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IGFBP-7 expression in human breast cancer and association with proliferation and cell cycle aberrations

✍ Scribed by H Östlund, A Burger, A Seth, G Landberg

Book ID
120700624
Publisher
BioMed Central
Year
2000
Tongue
English
Weight
298 KB
Volume
2
Category
Article
ISSN
1465-5411

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Insulin-like growth factors (IGF-I and -II) play an active role in cell proliferation. In biological fluids, they are non-covalently bound to high-affinity binding proteins (IGFBPs), at least 6 species of which have been identified to date, but with poorly defined functions. One of these IGFBPs, IGF