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IGFBp-3 prolongs the p53 response and enhances apoptosis following UV irradiation

โœ Scribed by Andrew D. Hollowood; Teresa Lai; Claire M. Perks; Paul V. Newcomb; Derek Alderson; Jeff M.P. Holly

Book ID
101334017
Publisher
John Wiley and Sons
Year
2000
Tongue
French
Weight
144 KB
Volume
88
Category
Article
ISSN
0020-7136

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We are exposed constantly to potentially harmful compounds and radiations. Complex adaptive protective responses have evolved to prevent such agents causing cellular damage, including potentially oncogenic mutation. The p53 tumour suppressor appears to have a role in coordinating such responses: it