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IGF-I(CA) repeat polymorphisms and risk of cancer: a meta-analysis

✍ Scribed by Xin Chen; Jianming Guan; Yuting Song; Peilin Chen; Hongxia Zheng; Cheng Tang; Qihan Wu

Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
432 KB
Volume
53
Category
Article
ISSN
1435-232X

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## Abstract IGFs are peptide hormones involved in the regulation of cell proliferation, differentiation and apoptosis. IGFs are regulated by endocrine and paracrine mechanisms; however, their action in tissue is determined by circulating levels and local production of IGFs and IGF‐binding proteins