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IGF-I therapy in the mature ovariectomized rat

โœ Scribed by D. Chachra; M. D. Grynpas; J. M. Lee

Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
144 KB
Volume
6
Category
Article
ISSN
0937-941X

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โœ E.I. Barengolts; T. Kouznetsova; A. Segalene; P. Lathon; C. Odvina; S.C. Kukreja ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› American Society for Bone and Mineral Research ๐ŸŒ English โš– 867 KB

Local and systemic insulin-like growth factors (IGFs) may be involved in the regulation of bone formation by sex hormones. The present studies describe the in vivo effects of estradiol, progesterone, or both on IGF-1 mRNA abundance in bone, serum IGF-1 levels, and bone formation. Rats were sham-oper