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IGF-1 up-regulates K+channels via PI3-kinase, PDK1 and SGK1

✍ Scribed by N. Gamper; S. Fillon; S. Huber; Y. Feng; T. Kobayashi; P. Cohen; F. Lang


Book ID
106109043
Publisher
Springer
Year
2001
Tongue
English
Weight
181 KB
Volume
443
Category
Article
ISSN
0031-6768

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Regulation of the voltage gated K+ chann
✍ G. Henke; G. Maier; S. Wallisch; C. Boehmer; F. Lang πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 126 KB

## Abstract The stimulation of cell proliferation by insulin like growth factor IGF‐1 has previously been shown to depend on activation of voltage gated K^+^ channels. The signaling involved in activation of voltage gated K^+^ channel Kv1.3 includes the phosphatidylinositol‐3 (PI3) protein kinase,